Reacción a "Controversy over the Trump administration's proposal of leucovorin as a treatment for autism"

The evidence about the use of leucovorin as a treatment for autism, either provided in pregnancy or to children with autism, is preliminary and requires stronger scientific studies to ensure safety and effectiveness. There are some promising studies suggesting possible benefits, but these studies have many limitations that suggest that further research is needed. They are not at the quality that is needed for widespread use. 

There are also some studies suggesting negative side effects. More work is needed to be certain about the correct dose and timing, particularly when given in pregnancy and early childhood, before being taken up as a treatment for the community. 

At a time when scientific research has been severely underfunded and challenged internationally, this work further highlights the importance and need for high quality scientific studies that can provide data to governments, policy makers, health practitioners and families about evidence-based practice.