Reacción a "Nobel Prize in Medicine or Physiology awarded to Ambros and Ruvkun for the discovery of microRNAs and their role in gene regulation"

It seems to me a well-deserved Nobel Prize. The two laureates discovered small RNA molecules that post-transcriptionally regulate gene expression of the vast majority of genes. Ruvkun and Ambros identified these molecules by studying the development of the nematode C. elegans when they observed that a small RNA molecule, Lin-4, suppressed the expression of Lin-14 during the development process of this organism. Altered expression of these molecules is associated with numerous pathophysiological processes, including cancer, neurodegenerative and cardiometabolic diseases. The possibility exists to manipulate the expression of these molecules for the treatment of these diseases. On the other hand, the discovery of microRNAs is a very relevant finding, since these molecules control numerous basic cellular and physiological processes such as development, cell proliferation and cholesterol metabolism.