Autor/es reacciones

Óscar Larrosa

Clinical neurophysiologist, expert in sleep medicine and clinical care manager of the Sleep Medicine Unit at MIP Salud-Personalised Comprehensive Medicine

Overall, it's an impeccable review of the evidence and the state of the art, of high quality, in my opinion.

It points out what was already suspected or known: in young children, melatonin is increasingly used as a quick fix for insomnia without studying the underlying problem, despite insufficient evidence of its overall usefulness, especially in the long term. And its potential long-term repercussions are not sufficiently documented.

The problem, as well pointed out, may lie in the over-the-counter sale of melatonin in many countries, which facilitates its use as a magic bullet and easy remedy (perhaps for parents), which is not advisable in biology and medicine if the causes in normally developing children are not studied. Its efficacy and usefulness are validated in longer-term neurodevelopmental problems, but this is not applicable to children with insomnia who are developing normally. Its use only seems reasonable in certain cases, for short-term, early-stage insomnia and at relatively low doses, as a precaution and because much about this neuroendocrine hormone remains unknown.

I don't see any major limitations in the article, but rather many strengths.

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