Autor/es reacciones

Rosa Fregel Lorenzo

Associate Professor

Head of the Evolution, population genetics and paleogenomics research group

This study led by Rohrlach demonstrates the great potential of paleogenomic techniques to study the past. In this case, the team used genomic data to identify individuals from the past who had any of the three trisomies that are not fatal in humans: Down syndrome (chromosome 21 trisomy), Edwards syndrome (chromosome 18) and Patau syndrome (chromosome 13). From a database of almost 10,000 individuals, they determined that six infants had Down syndrome and only one had Edwards syndrome. Although previous studies, such as the one published by Cassidy in 2020 and more recently in 2024 by Anastasiadou, had already identified older individuals with Down's syndrome, this is the first time the presence of Edwards' syndrome has been discovered. Perhaps most interestingly, three of the six cases of Down's syndrome and the one case of Edwards' syndrome have been detected in Iron Age sites in Navarra, in intramural burials of newborns. Given that the funerary practices of this population included the cremation of human remains, it is interesting that these children were buried differently and with great care in all cases. 
 
I believe that the study is based on robust data and analysis, and that its conclusions are supported by its results. I do not think there are any limitations to be considered.

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