Reacción a "The most extensive gene expression map of the prefrontal cortex suggests that the maturation process is completed around age 24"

This batch of papers is another outcome of the BRAIN Initiative launched by Obama in 2013—an initiative that continues to move forward regardless of changes in the presidency or the political climate.

This is high-quality work that employs single-cell transcriptomics to map cell types in the human prefrontal cortex. It meticulously applies methods previously established by other groups—following in the footsteps of the Allen Institute in Seattle (USA), which pioneered the use of these techniques to map cell types in both mouse and human cortices. Nevertheless, the study remains significant, as information regarding cell types is essential for understanding how neuronal circuits function.

Mapping every cell type in the brain was Cajal’s dream, and doing so in the human prefrontal cortex is particularly important, as this region is the hub for cognitive and mental information processing.