Reacción a "Intermittent fasting weight loss comparable to that of calorie restriction diets"

The study is well executed, and results are presented in a balanced way reflecting the results of the analysis.  The press release is also well written and is in line with the evidence in the field, that any strategy reducing calorie intake results in a proportional weight loss, either at each meal (CER) or by skipping meals (intermittent fasting). The missing additional benefit on cardiovascular risk markers of any intermittent fasting schemes aligns with our study that indicated that much longer periods fasting would be needed to change those.  However, we’ve seen that even those reverse quickly to levels seem before the intervention. 

One point to stress might be the rather moderate level of weight loss achieved with any intervention and the missing long-term follow-up in terms of weight maintenance and reduction in the onset of major diseases. For example, all dietary regimens, including the different forms of intermittent fasting, are unlikely to be sustainable. A fact also indicated by the decline in adherence in most studies. 

In brief, eating less leads to weight loss, irrespective on how you do it. Aspects that are missed but would have been of interest, are any effects on muscle mass, which is a major concern for current pharmacological interventions on obesity.