Reacción a "Reactions to study that identifies cells responsible for colon cancer relapse "

The study by Dr. Eduard Batlle's group is of high scientific and clinical quality and relevance. The work identifies for the first time a single population of tumor cells (which they call CRH) that expresses most of the markers of poor prognosis in patients. Furthermore, this work demonstrates that a small number of these HRC cells may already be present in distant organs such as the liver at the time of surgery and are responsible for producing the metastatic lesion. More importantly, elimination of the HRC cells is sufficient to prevent the generation of metastases after surgery. The fact that this cell population may be sensitive to immunotherapy suggests that the results obtained will have a major impact on clinical practice in the very short term.