Reacción a "Reactions of Spanish immunologists to vaccination strategy based on successive boosters in the general population"

As a generalised strategy for the whole population, a strategy based on boosters every few months is nonsense from an immunological point of view. As a strategy for vulnerable groups it may make sense, but it would be highly advisable to update the vaccine to the omicron variant and focus the booster only on this population group and with close monitoring of the loss of vaccine effectiveness. I very much miss studies of cell-mediated immunity + Ac, in this vulnerable group of patients in whom we need to know at what point they lose protection against the virus.

However, I doubt that giving boosters every few months is harmful. Our immune system is prepared to respond to a multitude of stimuli at the same time. But the secondary reactions to vaccination (adenopathies for example) would multiply, as would reactogenicity to the vaccine, discomfort, etc. Repeated boosters in the general population would only lead to a massive rejection of vaccination, and we would turn the success of the vaccination programme (in our country) into a failure due to the senseless abuse of vaccines.