University Clinical Hospital of Santiago

In recent decades, the rate of pollen allergies has increased worldwide. One of the reasons being considered is the increase in atmospheric nitrogen pollutants. Now, a study published in the journal The Lancet Planetary Health estimates that grasslands fertilised with nitrogen release six times more pollen and that this pollen is five times more allergenic than that from unfertilised fields.

According to a new study published in Science, a machine learning-based artificial intelligence (AI) system - called Mal-ID - can decipher an individual's history of infections and diseases in the immune system. The authors say this provides a powerful tool with the potential to accurately diagnose autoimmune disorders, viral infections and vaccine responses.

A team led by the CEU San Pablo University has analysed the role of vaccination against influenza on the risk of infection and mortality. The meta-analysis, published in European Respiratory Review, includes 192 articles from different countries over the last 20 years and includes data from more than 6.5 million patients. The results show that the level of protection varies according to age group and influenza subtype. Although it does not reduce the risk of infection for influenza A H3N2 in those over 65 years of age, nor does it show a reduction in mortality for influenza B - which is less associated with mortality than influenza A - overall, vaccination is shown to be effective in both preventing infection and reducing mortality.

An analysis of the gut microbiota of children growing up on farms or with pets shows that early establishment of anaerobic commensal bacteria is associated with lower rates of allergy later in life. The study, which used data from 65 children aged between three days and 18 months, is published in the journal PLOS ONE. 

Antimicrobial resistance caused around 5 million deaths worldwide in 2019. The use of vaccines has the potential to reduce these deaths - 515,000 fewer deaths per year - according to a report published by the WHO. The work focused on 24 pathogens and 44 vaccines, licensed by regulatory agencies, in clinical development or in development. By counting existing vaccines alone, antibiotic use could be reduced by 142 million daily doses per year.  

Toledo and Alicante are suffering the first outbreaks of measles recorded in Spain since the pandemic, El País reported today. In total, 15 cases have been confirmed since 1 January, of which seven are imported and eight autochthonous.

The Karolinska Institute has awarded the Nobel Prize in Medicine or Physiology to Katalin Karikó and Drew Weissman for their groundbreaking discoveries, which have radically changed our understanding of how mRNA interacts with our immune system, and made it possible to develop vaccines at unprecedented speed during the covid-19 pandemic.

The European Medicines Agency (EMA) has licensed Hipra's vaccine - currently called Bimervax - against SARS-CoV-2 as a booster in people aged 16 years and older who have previously been vaccinated with mRNA vaccines. The EMA began the ongoing evaluation of the vaccine, which was expected to be approved in the middle of last year, on 29 March 2022.

In recent weeks, the UK Health Safety Agency has detected an unusual increase in infections with Streptococcus pyogenes bacteria. At least 13 children under the age of 15 have died from this pathogen, which is responsible for mild infections but also for more serious conditions such as invasive disease. The Spanish Society of Paediatric Infectious Diseases has reported that there have been some deaths in Spain - the Community of Madrid has reported two deaths - and is analysing whether there has been an unusual increase in cases. 
 

During Pfizer's appearance before the European Parliament this week, a company executive responded to the question of whether "Pfizer's vaccine was tested to stop transmission of the virus (SARS-CoV-2) before going to market" by saying "no".