vaccines

The Pfizer-BioNTech COVID-19 vaccine has been linked to rare cases of heart inflammation in children and young people. The largest study of these risks in children, published in The Lancet Child & Adolescent Health, concluded that receiving the vaccine is associated with a risk of developing myocarditis or pericarditis within six months of 0.85 additional cases per 100,000 vaccinated children; while after COVID-19 infection, the risk is 2.24 additional cases per 100,000. The study used data from 98% of the British population under the age of 18 (almost 14 million) between January 2020 and December 2022.

Childhood vaccination rates have increased modestly worldwide in 2024, without reaching their pre-COVID-19 pandemic levels, according to data from the WHO and UNICEF. For example, global measles vaccination coverage rose by one percentage point from the previous year, reaching 84% of girls and boys who had received one dose in 2024, compared to 86% in 2019.

With the summer holidays approaching, questions arise about how to prepare for trips to other countries, including health recommendations. In this guide, we explain the basics of how to protect yourself and others.

Between 1980 and 2023, childhood vaccination rates against diphtheria, tetanus, whooping cough, measles, polio and tuberculosis doubled worldwide, according to a study published in The Lancet. However, this increase slowed in many countries between 2010 and 2019; during this period, measles vaccination declined in half of all countries.

Gonorrhoea is the second most common sexually transmitted disease in the world, with 80 million cases each year. There is no effective vaccine, and the bacteria responsible are becoming resistant to common antibiotics. Some studies have suggested that the meningococcal B vaccine, a unrelated bacterium, may offer partial protection against gonorrhoea. Now, an Italian team has identified 17 antibodies that could explain this cross-immunity, which, according to the authors, could be used to develop treatments and vaccines. The results are published in the journal Science Translational Medicine.

According to the results of a phase 2 trial, an oral norovirus vaccine generated a strong mucosal immune response and even reduced viral shedding in vaccinated volunteers. Signs of the vaccine's efficacy support its potential to address the lack of safe and reliable vaccines against this virus, which is a major cause of gastrointestinal infections worldwide. The results were published today in the journal Science Translational Medicine.

An Australian team has conducted a study involving mice and humans that suggests that vaccine boosters would be more effective if administered in the same arm as the previous dose, at least in the short term. However, other recent research has pointed in the opposite direction. The results are published in the journal Cell.

If immunisation rates continue to decline over an extended period, measles and even other eradicated diseases—such as rubella and polio—could re-emerge in the United States at endemic levels, according to a new study published today in the journal JAMA.

A study published in Nature magazine analysed the medical records of elderly Welsh men and women and discovered that those who had been vaccinated against shingles were 20% less likely to develop dementia in the following seven years. This effect was greater in women. The findings support the theory that viruses that affect the nervous system can increase the risk of dementia.

From 1 January to 23 February 2025, more than half as many cases of measles had already been reported in Spain as in the previous year. To analyse the causes of this spike, assess the seriousness of the situation and the measures to be taken, the Science Media Centre Spain organised a briefing with Noemí López Perea, researcher at the National Epidemiology Centre (CNE-ISCIII), Fernando Moraga-Llop, paediatrician, spokesperson and senior member of the Spanish Vaccinology Association (AEV), and María del Mar Tomás, spokesperson of the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC).