cancer

cancer

cancer

Reactions to trial using CAR-T cells prepared from donors to treat multiple myeloma

Approved therapies to treat various tumours using CAR-T cells are based on the modification of the patient's own lymphocytes in the laboratory, which delays their administration. A phase 1 clinical trial has used ready-made donor cells to treat patients with multiple myeloma. The results are published in the journal Nature Medicine.

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Reactions: two studies add circuitry to CAR-T cells to improve immunotherapy

Two preclinical studies published in the journal Science have introduced new bioengineered modifications to CAR-T cells in an attempt to make them more potent and safer in their anti-tumour action. These variations allow their activity to be enhanced only in the vicinity of the tumour or their actions to be regulated on demand.

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Reaction: expert group warns of cancer epidemic in Europe in the next decade if health and research do not improve

A panel of experts set up by the journal The Lancet Oncology analyses the impacts of the covid-19 pandemic on cancer treatment and research and makes recommendations to mitigate these problems. With an estimated one million cancer diagnoses lost across Europe in the past two years, the team warns that the continent is heading for a cancer epidemic in the next decade if health systems and cancer research are not urgently prioritised. 

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Reactions to the case study of a person who has survived twelve tumours

A study published today in Science Advances describes the case of a person who in less than 40 years of life has developed twelve tumours, five of them malignant, due to inherited mutations in a gene. The research reveals that his  immune system has naturally generated an altered inflammatory response that fights tumours. Understanding the mechanism will be useful to stimulate this type of response in other cases, according to the CNIO authors of the study.

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