cancer

A study published in the journal BMJ Oncology shows a preliminary stage test for the detection of 18 solid tumors of different organs based on the blood plasma proteome.

A dose of psilocybin—a hallucinogenic substance—administered to groups of 3 or 4 people suffering from cancer and depression may help reduce their depressive symptoms, according to a clinical trial conducted in the United States. The study involved 30 patients who also received individual and group therapeutic support. In another article, also published in the journal Cancer, the authors examine how the study participants perceived the therapy.

The US Food and Drug Administration (FDA) has issued a statement reporting that it has received reports of T-cell tumours in patients who received various CAR-T cell treatments. As quoted in the statement, "although the overall benefits of these products continue to outweigh their potential risks for their approved uses, FDA is investigating the identified risk of T cell malignancy with serious outcomes, including hospitalization and death, and is evaluating the need for regulatory action".

A fatty acid present in the meat and dairy products of grazing animals, such as cows and sheep – trans-vaccenic acid (TVA) – enhances the ability of CD8+ T cells to infiltrate tumors and eliminate cancer cells, according to a new study conducted by researchers from the University of Chicago (USA), published today in the journal Nature.

An international study involving ISGlobal in Barcelona has studied almost one million people and concludes that having a CT scan before the age of 22 increases the risk of developing blood tumours in later years by 16%. According to the authors, who publish the results in the journal Nature Medicine, "in terms of absolute risk this means that, for every 10,000 young people who undergo a CT scan, we can expect to see around 1-2 cases of cancer in the 2-12 years following the examination.

A machine learning model can use data on people's age, duration of smoking addiction and number of cigarettes smoked per day to predict lung cancer risk and identify who needs to be screened, according to a new study published in PLOS Medicine.

On the occasion of World Cancer Research Day on 24 September, the Science Media Centre Spain organised an information session on mass screening. At the meeting, researchers Adrian Aginagalde, Isabel Portillo and Juan Carlos Trujillo explained how mass screening is studied, analysed its advantages and disadvantages, explained how its implementation is decided and what new developments we can expect.

A standard chemotherapy drug injures surrounding noncancerous cells, which can awaken dormant cancer cells and promote cancer growth, according to a study published today in the journal PLOS Biology.

Since 1990, the incidence and deaths from early-onset cancers in teenagers and young adults have substantially increased worldwide. These are the main findings of a study published today in the BMJ Oncology journal.

A US study measures the risk of breast cancer overdiagnosis in screening campaigns for women over 70. These are women who are misdiagnosed with cancer after a mammogram, leading to unnecessary treatments that can cause complications, anxiety and financial costs. The study includes more than 54,000 women over the age of 70 who have had a screening mammogram. The retrospective analysis compares the cumulative incidence of breast cancer between two groups: women who continued screening up to 15 years later, and women who did not. The research estimates that 31% of breast cancer cases in women aged 70-74 result from overdiagnosis: it finds 6.1 cases per 100 women who had continued screening, compared with 4.2 cases per 100 women in the second group. The percentage of overdiagnosis increases with the age of the women. The article is published in the Annals of Internal Medicine, along with an editorial.