Alberto Ortiz Lobo
Doctor of Medicine and Psychiatrist at the Carlos III Day Hospital - La Paz University Hospital (Madrid)
The purpose of this research is to better differentiate psychiatric diagnoses by considering their genetic characteristics, because the clinical reality is that the expression of human suffering is complex and diverse, leading to a person receiving several diagnoses simultaneously, or diagnoses changing throughout their follow-up. To this end, they employ various genomic analyses in a sample of over one million people with diagnoses grouped into fourteen categories.
The findings have no impact on clinical practice, but they continue to support the promising idea that psychiatric diagnoses can be anchored to biological variables.
Psychiatric diagnoses, the subject of this type of research, are considered facts of nature, when in fact they are subjective clinical judgments made, moreover, based on the subjectivity of individuals: we lack hard, objective, and unequivocal data to confirm them. Psychiatric diagnoses are social constructs made by consensus, which change in number and definition in successive editions of diagnostic manuals, overlap with each other, and are conditioned by cultural and social factors, so that their genetic correlation is necessarily imprecise, as this study shows.