La Paz University Hospital

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SMC participants

Doctor of Medicine and Psychiatrist at the Carlos III Day Hospital - La Paz University Hospital (Madrid)

Head of the Paediatric Haematology-Oncology Department at the Hospital Universitario La Paz.

Head of Section of the Hospital Paediatrics, Infectious and Tropical Diseases Department of the Hospital Universitario Infantil La Paz (Madrid)

Clinical laboratory geneticist in the Molecular Ophthalmogenetics section of the Institute of Medical Genetics (INGEMM) and Molecular Genetics of the Hospital Universitario La Paz

Head of the Cancer Epigenetics Laboratory at INGEMM and coordinator of Experimental Therapies and Biomarkers in Cancer at IdiPAZ, La Paz University Hospital

Cardiologist at the Hospital Universitario La Paz, representative of the Spanish Society of Cardiology in the National Committee for the Prevention of Smoking and member of the Tobacco Expert Group of the World Heart Federation

Contents related to this centre
Apps and depression

Apps developed to treat depression may be beneficial in the management of severe and moderate cases. This is the conclusion of a review and meta-analysis that included 13 studies with up to 16 different apps. The results are published in the journal JAMA Network Open.


A phase 1 clinical trial has tested the use of psilocybin to treat anorexia nervosa. Ten women with the disorder were given 25 milligrams of the hallucinogen along with psychological support. The results show that the treatment is safe and tolerable. Four patients showed an improvement, but the authors acknowledge that, because of the small sample size and the absence of a control group, "the results are preliminary and further research is needed". The results are published in the journal Nature Medicine.


A commentary published last Friday in the journal Molecular Psychiatry, signed by more than 30 researchers, challenges the conclusions of the systematic review published in the same journal in July 2022, in which the authors concluded that there was no evidence that low serotonin levels cause depression. The researchers in the new paper blame the earlier study for flaws in methodology, among other weaknesses.


On 5 April, the UK National IHR Focal Point informed WHO of an increase in severe myocarditis in neonates associated with enterovirus infection in Wales (UK). Between June 2022 and April 2023, ten hospitalised neonates with a positive PCR for enterovirus were found to have myocarditis. Seven of the ten cases were confirmed to have coxsackievirus B3 or coxsackievirus B4. As of 5 May 2023, one patient remained hospitalised and one patient had died. According to the WHO statement, although enterovirus infections are common in neonates and infants, the reported increase in myocarditis - inflammation of heart muscle tissue - with severe outcome associated with enterovirus infection is unusual.


A phase 2 clinical trial has analysed the safety and efficacy of adding immunotherapy to traditional chemotherapy to treat a subtype of acute lymphoblastic leukaemia in children under one year of age. This subtype of leukaemia, although rare in absolute terms, is the most common in children of this age, and its prognosis in this age group had not improved in recent years. The immunotherapy used, a bispecific antibody that binds to tumour cells on the one hand and T lymphocytes on the other, improved two-year survival from 66% to 93% in treated patients, according to The New England Journal of Medicine (NEJM).

lung cancer

Seven studies published in Nature and Nature Medicine look at how lung cancer evolves, with genomic studies of more than 1,600 tumour samples taken from 421 patients in the TRACERx project. The research includes the most common type of lung cancer (NSCLC) and assesses why tumours sometimes recur, spread to other parts of the body or the effects of platinum-based chemotherapy.


Using genetic data from more than 340,000 participants of European descent, research has identified five genetic variants that make people more susceptible to myopia in combination with intensive schooling, especially university studies. The results are published in PLOS Genetics.


A study published in the journal Nature Communications in mice has associated the inhalation of e-cigarette aerosols with heart rhythm disorders, including ventricular arrhythmias.