neuroscience

neuroscience

neuroscience

Deep brain stimulation improves walking after spinal cord injury

According to a study published in Nature Medicine, deep brain stimulation of the lateral hypothalamus improves walking and promotes recovery in humans and rodents with spinal cord injuries. In humans, the authors tested this technique on two patients who relied on assistive devices and had difficulty walking; both showed improved performance in the ten-meter and six-minute walking tests. Combined with rehabilitation, the patients experienced recovery that persisted even after the deep brain stimulation was turned off.

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Astrocytes, like neurons, would also store memories

Until now, memories have been explained by the activity of neurons that respond to learning events and control recall. A study published in Nature changes this theory by showing that non-neuronal cells in the brain called astrocytes - star-shaped cells - also store memories and work in concert with clusters of connected neurons called engrams to regulate the storage and retrieval of memories.

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Imaging study details changes in a woman's brain during and after pregnancy

A study describes changes in a woman's brain during and after pregnancy, including a ‘pronounced’ decrease in grey matter volume and cortical thickness, and an increase in ventricular volume and cerebrospinal fluid. Some of the changes are maintained in the postpartum period; others reverse within months. The team performed 26 MRI scans and blood tests on one mother, from pre-conception until two years postpartum, and publish the results in Nature Neurology

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One in four people with brain-damage who do not respond to stimuli may have some degree of consciousness

An international team of researchers has studied 241 brain-damaged people apparently unable to respond to external stimuli. Using techniques such as functional magnetic resonance imaging and electroencephalogram, they have detected signs of brain activity in 25 % of them that, according to the authors, ‘suggest that they may be interacting with the outside world’. The results are published in the journal NEJM

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Classical music's antidepressant mechanism in the brain studied

A brain study of 23 people with treatment-resistant depression while they listen to classical music has identified the antidepressant mechanisms of this music. Using intracranial recordings and electroencephalogrammes, the researchers concluded that listening to classical music synchronises neuronal oscillations between the auditory cortex - responsible for processing sensory information - and the reward circuit - responsible for processing emotional information. "The improvement of depressive symptoms was not linked to the emotion of the music itself but was correlated with the patient’s level of music enjoyment," says the study published in Cell Reports.

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Sex and gender are associated with distinct brain network patterns

Both sex and gender are associated with distinct networks in the brains of boys and girls, according to an analysis of brain images of 4,757 children in the US. Understanding these neurobiological patterns is important for identifying how sex and gender influence health and for developing specific diagnostic tools, the research team writes in Science Advances.

 

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Changes observed in brain images of adolescents with internet 'addiction'

Internet 'addiction' in adolescents is associated with changes in neural networks in their brains, a review of studies has found. The analysis published in PLoS Mental Health brings together the results of 12 previous functional magnetic resonance imaging studies, conducted in young people aged 10-19 in Asian countries (Korea, China and Indonesia).

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A global consortium analyzes neuropsychiatric diseases cell by cell

The PsychENCODE consortium, established in 2015 and dedicated to illuminating the molecular mechanisms underlying schizophrenia, bipolar disorder, and autism spectrum disorder, presents findings based on the examination of human brains at the cellular level. The studies are published today in the journals Science, Science Translational Medicine and Science Advances.

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Non-invasive electrostimulation device improves arm and hand function in quadriplegic patients

A clinical trial involving 60 people with upper and lower body paralysis showed that a non-invasive electrical spinal cord stimulation device - called ARCEX - helps improve hand and arm function in quadriplegic patients. The study, the results of which are published in Nature Medicine, showed that 43 of the people with paralysis experienced improved arm and hand strength and function after receiving electrical stimulation along with rehabilitation exercises.  

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