ageing

ageing

ageing

Increasing proportion of older people exposed to heat that is hazardous to their health

Twenty-three per cent of the world's population over the age of 69 will be living with acute heat exposure by 2050, compared to 14 per cent in 2020, according to a study published in Nature Communications. The research highlights southern Europe, parts of North and South America, Southeast Asia and all of Australia as areas of ‘increasing stress’, where higher heat exposure overlaps with an increasingly ageing population. The effects will be most severe in Asia and Africa, according to the study. 

0

What is Prospective Age and Why Does it Give us a Different View on Heat-Related Mortality?

Until now, it was thought that the risk of heat-related death in Spain had decreased among older people. But what if we take into account the increase in longevity? Has it decreased as much as the studies suggested? In this case it is useful to use the concept of prospective age, i.e. the years we hypothetically have left to live, rather than the years we have lived. 

0

Reaction: Pregnancy is associated with an increase in biological age

Un estudio analizó la edad biológica de más de 1.700 participantes utilizando seis relojes epigenéticos diferentes. Los resultados mostraban que cada embarazo individual reportado por una mujer se correlacionaba con un envejecimiento biológico adicional de dos a tres meses. Estos efectos persistían incluso cuando se tenían en cuenta el estatus socioeconómico, el tabaquismo, la variación genética y la urbanidad del entorno de los participantes. El estudio se publica en PNAS

0

Reaction to study suggesting that accumulation of 'junk proteins' could be a possible cause of ALS

In a paper published in Molecular Cell, a team of researchers led by the Spanish National Cancer Research Centre (CNIO) provides the first evidence that a possible cause of the hereditary type of ALS - familial ALS - is the accumulation in motor neurons of 'junk proteins', proteins with no function that accumulate unduly and prevent the cell from functioning properly. In addition, the research describes a new causal factor in the ageing process: nucleolar stress, which encompasses alterations in organelles called nucleoli. 

0

Reaction: longevity gap between women and men is shrinking

Indicators of human longevity are on an upward trend in five groups of countries around the world, and the gap between women and men is narrowing, according to a study published in PLoS ONE. The gender gap in life expectancy resulting from the harmful effect of men's blue-collar jobs will shrink, but will persist in the future because men have a higher risk of certain diseases, the authors write. The research team, which includes scientists from the universities of Alcalá́, Barcelona, Oxford and London (UK), uses data and projections for 194 countries from 1990 to 2030.

0

Reactions to the study associating hearing loss with a higher risk of dementia

A Danish study involving over half a million individuals aged 50 and above, tracked for an average of nearly nine years, reveals that hearing loss is associated with a higher risk of dementia, particularly among those who do not use hearing aids. According to the authors, whose research is published in JAMA Otolaryngology–Head & Neck Surgery, this suggests that hearing aids may prevent or delay the onset and progression of dementia.

0

Reactions: blood test can measure organ age

A study of more than 5,000 patients has developed a method to predict the biological age of our organs. They have analysed more than 4,000 proteins present in the blood and used machine learning models adapted to 11 different organs. According to the authors, almost 20 % of the population has accelerated organ ageing, which in many cases is associated with an increased risk of mortality of between 20 and 50 %. The results are published in the journal Nature.

0

Reactions: study links living as a renter to faster biological ageing

Living as a private renter is associated with faster biological ageing than owning a home, according to a study using a UK database with data available on 1,420 people. The team, whose research is published in the Journal of Epidemiology and Community Health, used DNA methylation data - chemical modifications - to measure people's biological age, and says this correlation is stronger than the association between biological ageing and unemployment, or having been a smoker. Apart from blood samples from the database, the research also used historical data from a national survey.

0

Reactions: klotho protein administration improves memory in aged macaques

Klotho is a protein whose concentrations tend to decline with age and which has been linked to ageing processes. Now, researchers have found that administration of the protein improves cognitive function in aged rhesus macaques, including benefits in spatial and working memory. According to the authors, who publish the results in the journal Nature Aging, its use "may be therapeutic in humans".

0