psychiatry

psychiatry

psychiatry

A global consortium analyzes neuropsychiatric diseases cell by cell

The PsychENCODE consortium, established in 2015 and dedicated to illuminating the molecular mechanisms underlying schizophrenia, bipolar disorder, and autism spectrum disorder, presents findings based on the examination of human brains at the cellular level. The studies are published today in the journals Science, Science Translational Medicine and Science Advances.

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Children of people with mental disorders are more at risk of developing the same or other disorders

The largest meta-analysis to date that studies the risk of children of people with a mental disorder also suffering from some type of mental disorder during their lifetime has been published, with Spanish participation. According to the study, the risk is more than double that of the rest of the population. To explain the study and resolve any doubts that may arise, the Science Media Centre Spain organised an information session with one of the authors, psychiatrist Joaquim Raduà.

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Reactions: study warns of low treatment rates for mental disorders in children and adolescents

A meta-analysis, pooling the results of 40 previous studies - involving more than 310,000 children and adolescents in total - concludes that treatment rates for mental disorders in these age groups are "generally low, especially for depression and anxiety". The research, published in JAMA Network Open, shows that the treatment rate for any mental disorder is 38%, ranging from 31% for anxiety, 36% for depression, 49% for conduct disorders and 58% for attention deficit hyperactivity disorder (ADHD).

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Reactions to the phase 1 clinical trial studying the use of the hallucinogen psilocybin for anorexia

A phase 1 clinical trial has tested the use of psilocybin to treat anorexia nervosa. Ten women with the disorder were given 25 milligrams of the hallucinogen along with psychological support. The results show that the treatment is safe and tolerable. Four patients showed an improvement, but the authors acknowledge that, because of the small sample size and the absence of a control group, "the results are preliminary and further research is needed". The results are published in the journal Nature Medicine.

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Reactions: 30 researchers challenge study questioning the hypothesis that low serotonin levels cause depression, published last year

A commentary published last Friday in the journal Molecular Psychiatry, signed by more than 30 researchers, challenges the conclusions of the systematic review published in the same journal in July 2022, in which the authors concluded that there was no evidence that low serotonin levels cause depression. The researchers in the new paper blame the earlier study for flaws in methodology, among other weaknesses.

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Reaction: study claims it is possible to predict schizophrenia from fingerprints with 70 % reliability

Researchers from FIDMAG Hermanas Hospitalarias and CIBERSAM have announced the development of an algorithm that detects the risk of schizophrenia from fingerprints with a reliability of 70 %. It has been tested on 700 patients with schizophrenia and 850 people without schizophrenia; validation studies are pending.

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