Carlo Maley

Carlo Maley

Carlo Maley
Position

Director of the Arizona Cancer Evolution Center and Professor at the University of Arizona (USA)

Topics

Study shows that larger species do develop more cases of cancer, disproving Peto's paradox

Peto´s paradox is the lack of observed relationship between the size of an animal and the prevalence of cancer, despite the fact that the greater number of cells and divisions as they get larger should increase the likelihood of cancer. A new study disproves this paradox by finding that, at least in terrestrial vertebrates, larger species do develop more cases of cancer. In quite a few of them, however, the increase is less than would be expected, suggesting that they have evolved anticancer mechanisms that remain worth studying. The results are published in the journal PNAS.