Changes caused by diet, smoking, and exposure to pesticides are linked to the development of colorectal cancer in people under 50
A team from the Vall d'Hebron Institute of Oncology in Barcelona has published a study examining the impact of the exposome—changes in lifestyle and environmental factors—on early-onset colorectal cancer through epigenetic signatures. By analyzing methylation patterns in patients, they confirmed previously identified risk factors such as diet, educational level, and tobacco use. Additionally, they identified a significant association with picloram, a widely used herbicide. The results are published in Nature Medicine.
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