Reacción a "Reactions: Breast cancer relapse may be triggered by chemotherapy damage to non-cancerous cells"

The methodology is adequate, but limited to preclinical models, so its translation to the clinic remains to be determined.

This study adds to the growing evidence that chemotherapy can damage non-tumor cells that are part of cancers and specifically demonstrates that it can reactivate the growth of dormant tumor cells. Importantly, it describes mechanisms causing this tumor re-emergence in breast cancer that can be counteracted pharmacologically at an experimental level. Its clinical translation is still a question mark.