Reacción a "Reactions: gel stops brain tumors in mice"

The animal model on which the study is based is not at all representative of what a human glioblastoma is. They have worked with a murine cell line that was chemically induced with a series of alterations that morphologically mimic glioblastoma, but which at the molecular level have nothing to do with human glioblastoma. It is often used to study the effects of host immunity. But to claim that the immune reaction of the mouse to this experimental glioma is the same as that of the patient is a considerable leap of faith. There is still a long way to go before the therapy they propose can be tested in patients to assess first safety and then some kind of efficacy.