Reacción a "New neurons detected forming in adult human brains"

The article contributes significantly to knowledge about the process of adult hippocampal neurogenesis in humans. It has used sophisticated methodologies that provide unprecedented spatial resolution in this field and has helped identify a special type of cell, proliferative stem cells, using transcriptomic techniques.

The study uses two novel techniques, called single-nucleus RNA sequencing (snRNA-seq) and single-cell resolution spatial transcriptomics, together with machine learning. The application of these methodologies has allowed the identification of proliferative progenitor cells in the human hippocampus. These cells are very rare and very similar to glial cells, so the application of these techniques has been key to identifying them, something that previous studies had not been able to do.

[Regarding possible limitations] Any research based on the study of post mortem human samples has certain inherent technical limitations, but this study is a tour de force in the field.