Severo Ochoa Centre for Molecular Biology, UAM-CSIC

Nicolás Cabrera 1, 28049, Madrid

Alzheimer's, Antarctica / Arctic, astrobiology, big data, cancer, covid-19, embryonic development, gene editing, cardiovascular diseases, neurodegenerative diseases, rare diseases, ageing, epidemiology, immunology, microbiology, nanoscience, neuroscience, transgenics
María José Martin Pereira
Head of Communication and Scientific Culture

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SMC participants

Senior Scientist at the CSIC and researcher at the Centro de Biología Molecular Severo Ochoa

Virologist and immunologist at the Severo Ochoa Centre for Molecular Biology, coordinator of the CSIC interdisciplinary research platform on Global Health.

Contents related to this centre

The Karolinska Institute has awarded the Nobel Prize in Medicine or Physiology to Katalin Karikó and Drew Weissman for their groundbreaking discoveries, which have radically changed our understanding of how mRNA interacts with our immune system, and made it possible to develop vaccines at unprecedented speed during the covid-19 pandemic.


Taurine is one of the most abundant amino acids in animals. As reported in research published in Science, its loss may contribute to the ageing process. According to the study, reversing age-associated taurine deficiency through supplementation improved life expectancy in worms and rodents, while improving some health parameters in non-human primates, which the authors believe would warrant further human trials to examine its effect on life expectancy and the potential risks involved.

Laboratory mouse

Researchers have shown that hypoxia, or oxygen restriction - equivalent to living at 5,000 metres above sea level - increases life expectancy by up to 50% and decreases neurological decline in laboratory mice. It has already been shown in yeast, worms and flies, but this is the first time it has been demonstrated in mammals. The results are published in the journal PLOS Biology. 


Air pollution has been repeatedly linked to the risk of developing dementia. In addition to confirming this association, a study published in the journal PNAS has analysed the individual risk posed by the components present in PM2.5 fine particulate matter.


Two researchers propose that the anti-diarrhoeal drug Loperamide could be a candidate for treating the main symptoms of autism spectrum disorder (ASD), such as difficulties in social interaction and communication. The research, published in the journal Frontiers in Pharmacology, has used a computer model that includes the proteins involved in ASD and has analysed how different drugs affect them.


A study published in Cell Reports shows that air pollution and stress during pregnancy disrupt the brain wiring of developing male and not female mice, causing autism-like social behavior in them.