Spanish National Research Council (CSIC)

According to a study published in Nature Medicine, deep brain stimulation of the lateral hypothalamus improves walking and promotes recovery in humans and rodents with spinal cord injuries. In humans, the authors tested this technique on two patients who relied on assistive devices and had difficulty walking; both showed improved performance in the ten-meter and six-minute walking tests. Combined with rehabilitation, the patients experienced recovery that persisted even after the deep brain stimulation was turned off.

The seventh Annual Report of the COSCE Transparency Agreement, prepared by the European Animal Research Association, which analyses transparency in the use of animals for scientific experimentation in Spain in 2023, was presented today. According to the document, transparency is consolidated among the signatory institutions -168 in 2024- and all of them publish a statement on their websites on the use of animals. Public mention of the number and species used stands at 47%, compared to 38% the previous year.

The fifth session of the United Nations Intergovernmental Negotiating Committee to develop an international legally binding instrument on plastic pollution (INC-5) ended without a treaty in Busan, South Korea, in the early hours of the morning. The more than 100 countries participating in what was to be the final round of negotiations have agreed to continue negotiating, reports Reuters.

A study published today in Science reveals a new plastic as durable as conventional plastics that decomposes in seawater. According to the authors, this new material could help reduce microplastic pollution accumulating in the oceans and eventually entering the food chain.

The DANA that devastated the province of Valencia on 29 October, leaving more than 200 people dead and many missing, has been followed by another one, still located over the peninsula. How can we adapt to these extreme phenomena? What repercussions do they have on public health? How can the public prepare for them? The Science Media Centre España organised a briefing session with two experts and an expert from the CSIC to discuss these questions. 

If practices and public policies do not change, the mass of mismanaged plastic waste in the world will double to 121 million tonnes per year by 2050, according to a study published in Science. The article also assesses the potential impact of global measures, such as those envisaged by the forthcoming UN global treaty on plastic pollution, which begins its final negotiating session at the end of this month.

Less than four months after the European Medicines Agency recommended in July not to grant marketing authorisation for Leqembi™ (lecanemab) for the treatment of Alzheimer's disease, the EMA's Committee for Medicinal Products for Human Use (CHMP) has reassessed the available evidence to conclude that the benefits outweigh the risks.

Many diseases related to bacteria, such as inflammatory bowel disease or colorectal cancer, are associated with an overgrowth of gut bacteria considered 'bad'. However, a study published in the journal Cell suggests that changes in microbial load, rather than the disease itself, could be the driving factor behind the presence of these harmful species associated with pathologies.

Next Monday sees the start of COP29 in Baku, the capital of Azerbaijan, a summit marked by Donald Trump's victory as president of the United States on Tuesday. His denial of climate change and his commitment to fossil fuels during his previous term in office will weigh down a meeting from which no major agreements are expected and from which experts are calling for greater ambition. 

A team of researchers led by the Center for Genomic Regulation in Barcelona has mapped the human spliceosome for the first time. This complex and partially unknown cellular machinery is responsible for cutting and splicing the RNA fragments encoded by genes in different ways, making it possible to obtain a wide variety of proteins from the same sequence. Its alteration is related to processes such as cancer, neurodegenerative processes or various rare diseases. According to the researchers, who publish the results in the journal Science, “by knowing exactly what each part does, we can find completely new angles to address a broad spectrum of diseases”.