Spanish National Research Council (CSIC)

According to a report published yesterday in The New York Times, most of the members of the Subcommission on Quaternary Stratigraphy had rejected the proposal to declare the beginning of the Anthropocene, thus showing their opposition to the idea that this is a new geological epoch. Other sources told El País that the result of the vote was not formally confirmed. If this proposal is defeated, the process could be restarted from scratch at a later date.

Eating more ultra-processed foods is linked to a higher risk of health problems, according to an umbrella review of 45 previous meta-analyses, involving almost 10 million people in total. The research, published in The BMJ, finds direct associations between exposure to ultra-processed foods and 32 health parameters. The strongest evidence links this exposure to cardiometabolic health problems, mental disorders and overall mortality.

Epigenetic editing is a technique that aims to alter gene expression without the need to modify the DNA sequence, as gene editing techniques do. In this way, Italian researchers have succeeded in silencing the PCSK9 gene in mice, thereby reducing cholesterol levels by half for at least a year. According to the authors, and assuming further evaluation is needed, their platform "could lay the foundations for the development of this type of therapy". The results are published in the journal Nature.

Mercury concentrations in tuna have remained stable between 1971 and 2022, even though emissions of this metal from human activities have decreased over the same period, a study says. 'Aggressive' emission reduction targets are needed to achieve measurable declines in concentrations of this pollutant, which is toxic for human health, the authors write in the journal Environmental Science & Technology Letters. The Minimata Convention on Mercury, a global treaty that entered into force in 2017, bans new mercury mines and includes provision to reduce mercury use, but mercury has already accumulated in the ocean 'for centuries', the article says.

Cresomycin, a new synthetic molecule, exhibits robust efficacy against multiple evolutionarily divergent forms of antimicrobial resistance (AMR), according to a study published today in Science. By structurally analyzing how antibiotics bind to ribosomes of various bacterial species, researchers developed a new antibiotic molecule that adopts the exact conformation necessary for ribosomal binding.

The European Centre for Disease Prevention and Control (ECDC) reported that on January 29th, Spanish authorities notified a possible case of human infection with swine flu virus A(H1N1)v in a worker from a Catalan pig farm. After being diagnosed with bronchitis, subsequent laboratory analyses confirmed it as swine flu A(H1N1)v. The ECDC informs that the patient has fully recovered, and to date, no new cases have been detected among close contacts or among the worker's colleagues at the farm.

In 2010, nearly 1,000 sub-basins around the world were facing water shortages. But when considering not only water quantity, but also water quality, this figure rises to more than 2,500, according to a study published in Nature Communications. By 2050, the authors estimate that up to a third of sub-basins will face severe shortages of clean water, which could affect 3 billion people. Southern China, Europe, North America and Africa will be the most affected regions.

Fifteen years ago, the European Space Agency's (ESA) Mars Express probe revealed the presence of large deep deposits on Mars, in an area called the Medusae Fossae Formation (MFF), located at its equator. Now, new data from the probe's MARSIS radar indicate that the deposits are deeper than previously thought - up to 3.7 kilometers thick - and include both ice-rich and dusty layers. The results are published in Geophysical Research Letters.

A team of Chinese researchers report today in the journal Nature Communications the successful cloning of a rhesus monkey, with a healthy placenta, which survived for more than two years. According to the authors, this could improve the efficiency of the monkey cloning process, which so far is very low. Previously, different teams have cloned more mammalian species, including 'Dolly the sheep' and another species of macaque (Macaca fascicularis).

A team led by the Princess Máxima Pediatric Oncology Center and the Hubrecht Institute (The Netherlands) has generated small 3D brain models--known as organoids--from human fetal brain tissue. Until now, these brain organoids-which attempt to resemble real organs on a miniature scale-were grown in the laboratory using pluripotent or embryonic stem cells. The new technique, published in the journal Cell, allows regions of brain tissue to self-organize into three-dimensional brain structures. The authors used these organoids and the CRISPR-Cas9 tool to simulate the development of one type of brain tumor, glioblastoma, and see how it responded to different drugs.