Analia Bortolozzi

Analia Bortolozzi

Analia Bortolozzi
Cargo

Senior scientist at the Institute for Biomedical Research of Barcelona (IIBB-CSIC), principal investigator at CIBERSAM and head of the Systems Neuropharmacology group at IDIBAPS-Fundació Clínic.

Reactions: New technique tested to improve gene therapy for Parkinson's disease

A study led by Spanish researchers and published in Science Advances has tested a new technique to improve gene therapy treatments for Parkinson's disease. Using ultrasound, they have managed to open the blood-brain barrier in specific areas, allowing the viruses used in the therapy to pass through and better reach the desired brain areas. After testing it on monkeys and three patients -patients were not given gene therapy, but the efficacy of the technique was tested using a radiotracer that does not normally cross the blood-brain barrier-, their conclusions are that the technique is safe and feasible and "could allow early and frequent interventions to treat neurodegenerative diseases".

 

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