Reacción a "Reactions to study claiming three doses of covid-19 vaccines protect better than two"

This work is in line with what had already been observed about the efficacy of vaccines, both in preventing hospitalisation and infection, depending on the doses, the time after the dose, and the variant of the virus.  

It has the virtue of being a very large population-based study, across a whole country, which reinforces what was already known. As the authors themselves say, one limitation of the study is that, due to the timing, the results obtained against omicron may change if the new BA.4 and BA.5 variants are taken into account. It would be desirable for the study to be continued throughout 2022, in order to be able to evaluate this aspect. This would also extend the post-vaccination or post-reboot time in which efficacy against Omicron is assessed in a similar way to what has been done with other variants.