multiple sclerosis

An international team, involving researchers from Hospital Clínic-IDIBAPS and the Multiple Sclerosis Centre of Catalonia (Cemcat), has identified for the first time a genetic variant related to the progression of multiple sclerosis. It is located near two genes that had not previously been linked to multiple sclerosis. According to Stephen Sawcer, co-lead author of the study, "understanding how the variant exerts its effects on the severity of multiple sclerosis will pave the way for a new generation of treatments that can prevent disease progression". The results are published in the journal Nature.

A study of 89 patients has shown that the drug teriflunomide is able to delay the onset of multiple sclerosis symptoms in people whose MRI scans show early signs of the disease, even if they have not yet developed symptoms. The work has not yet been published in a scientific journal and its results have been shared at a meeting of the American Neurological Association.

A Swedish study has found an association between lack of sleep or poor quality sleep during adolescence and an increased risk of developing multiple sclerosis later in life. They put the relative increased risk at 40 %. The results are published in the Journal of Neurology, Neurosurgery and Psychiatry.