Autor/es reacciones

Andrés Moya

Professor of Genetics at the University of Valencia and researcher of the Genomics and Health Area at the Foundation for the Promotion of Health and Biomedical Research of the Valencian Community (Fisabio)

The study represents a significant advance in the construction of synthetic cells by integrating, within a single system, the processes of growth, nutrient uptake, DNA replication, gene expression and division. Rather than merely reproducing isolated cellular functions, the authors have succeeded in coordinating these activities within a functional cycle that approximates the behaviour of a minimal cell. The study constitutes a major milestone for synthetic biology and provides an experimental platform for investigating the organisational principles of life. However, it remains dependent on external components and conditions, and is therefore still far from achieving the metabolic and evolutionary autonomy of natural cells. Overall, the work represents an important step towards understanding and reconstructing the fundamental processes that characterise living systems. I consider this work an honour, not least because it cites one of my papers – from as far back as 2009, reference 12.
EN