Professor of Genetics at the University of Valencia and researcher of the Genomics and Health Area at the Foundation for the Promotion of Health and Biomedical Research of the Valencian Community (Fisabio)
The team led by scientist Kate Adamala of the University of Minnesota has released the news—under an embargo—to several media outlets regarding the creation of a synthetic cell capable of feeding, growing, and replicating, which they have named Spudcell. Their work, which, according to Science News, was rejected by the journal Cell, is published on the team’s website, pending peer review.
A team of researchers led by the Center for Genomic Regulation in Barcelona has mapped the human spliceosome for the first time. This complex and partially unknown cellular machinery is responsible for cutting and splicing the RNA fragments encoded by genes in different ways, making it possible to obtain a wide variety of proteins from the same sequence. Its alteration is related to processes such as cancer, neurodegenerative processes or various rare diseases. According to the researchers, who publish the results in the journal Science, “by knowing exactly what each part does, we can find completely new angles to address a broad spectrum of diseases”.