Andrés Moya

Cargo

Professor of Genetics at the University of Valencia and researcher of the Genomics and Health Area at the Foundation for the Promotion of Health and Biomedical Research of the Valencian Community (Fisabio)

University of Valencia, Foundation for the Promotion of Health and Biomedical Research of Valencia Region (FISABIO)

Topics

genetics

First mapping of the human spliceosome, the machinery that allows multiplying the variety of proteins from the same DNA

genetics

First mapping of the human spliceosome, the machinery that allows multiplying the variety of proteins from the same DNA

SMC Spain

A team of researchers led by the Center for Genomic Regulation in Barcelona has mapped the human spliceosome for the first time. This complex and partially unknown cellular machinery is responsible for cutting and splicing the RNA fragments encoded by genes in different ways, making it possible to obtain a wide variety of proteins from the same sequence. Its alteration is related to processes such as cancer, neurodegenerative processes or various rare diseases. According to the researchers, who publish the results in the journal Science, “by knowing exactly what each part does, we can find completely new angles to address a broad spectrum of diseases”.