Blocking a protein improves health and lifespan in mice
An international group of researchers has shown in mice that inhibiting an inflammatory protein called interleukin 11 improved the animals' metabolic status, health and frailty. In addition, it increased their life expectancy by an average of around 25%. These effects have not been tested in humans, but clinical trials are underway testing an antibody directed against the same protein to see if it benefits cystic fibrosis patients. The results of the new research are published in the journal Nature.
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