Head of the Hepatology and Liver Transplant Group, IIS La Fe. Coordinator of the Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD) group. President of the International Liver Transplant Society. Member of AMIT
Three studies published today in Nature explore the link between the cases of childhood hepatitis of unknown origin that have occurred since 2022 mainly in the UK and the US and an adeno-associated virus. The papers do not settle the question and further studies will be needed to confirm or exclude the hypothesis.
In recent weeks, several countries have detected unusually severe cases of hepatitis of unknown origin in healthy children. Some of the patients have required transplantation and at least one of them has died. Researchers are working on several hypotheses around an adenovirus, but the matter is still shrouded in uncertainty.
This week the European Centre for Disease Control and Prevention (ECDC) has warned of an increase in cases of hepatitis of unknown origin in children in the UK. Three cases have been diagnosed in Ciudad Real, Madrid and Aragon, one of which required a liver transplant. With the current information it is difficult to establish the cause.