Jerez hospital
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Director of the Pneumology and Allergy Clinical Management Unit of the Hospital de Jerez and lecturer at the University of Cadiz
An international team of researchers, with Spanish participation, has proposed in the journal Science a new mechanism to explain asthma attacks more fully. According to their hypothesis, the mechanical forces that occur during these episodes cause cells to accumulate in excess, leading to a process of elimination called "cell extrusion". As a result, the tissue is damaged, loses its barrier function and increases the risk of successive attacks. Inhibitors of this mechanism improved damage and inflammation in laboratory mice.