Reacción a "Reactions to the new mapping of rare disease diagnoses in Spain since 1960"

It is an interesting and unique study, in that it uses data from around 3,300 patients with a rare disease from the Spanish registry of patients with rare diseases between 1960 and 2021. The aim is to assess the delay in obtaining genetic diagnosis. A delay of just over six years on average is still far from the objectives of the International Rare Diseases Research Consortium (IRDiRC), which aims to achieve a diagnosis in less than a year from the time the patient requests medical care.  

Logically, the delay has been decreasing over the years, as technology has evolved. The conclusions of this study are on the other hand quite similar to previous studies, such as the three EnSerio studies (Study on the Situation of Social and Health Care Needs of People with Rare Diseases in Spain) carried out by the Spanish Federation for Rare Diseases (FEDER) in 2009, 2013 and 2017, based on interviews with patients (between 700 and 1600), the latest edition of which the authors cite.  

The delay in genetic diagnosis obtained in the EnSerio studies, on average, is also between four and six years. There are also comparable analyses carried out by the health departments of some autonomous communities. Hence, many researchers in this field have been indicating for some time now that the average delay in the genetic diagnosis of rare diseases in Spain is about five years. However, we should not forget that the number of people affected by a rare disease in Spain is around 3 million people. Therefore, it would be opportune to obtain data from larger cohorts of patients than any of the studies carried out so far. In short, a new confirmation that we need to make a greater effort in our country, to invest in personnel, resources and technologies, in order to meet the IRDiRC objectives that we have committed to achieve.