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An international team of researchers has conducted a meta-analysis of 137 clinical trials involving nearly 90,000 people to assess the migraine efficacy of 17 available drugs. Their conclusions are that four drugs in the triptan group are more effective and cheaper than newer drugs such as gepants or lasmiditan, and that the efficacy of the latter is comparable to that of paracetamol and most anti-inflammatory drugs. The results are published in The BMJ.

US researchers have analysed data from 477 people who, using a mobile app, recorded their moods, energy levels and migraine occurrence four times a day for two weeks. Morning attacks were associated with poorer self-rated sleep quality and less energy the day before. Stress and high-energy states were linked to headaches in the afternoon, adds the study, which is published in the journal Neurology.