neurology

Parkinson's disease is usually diagnosed when there is already extensive neuronal damage and symptoms are evident. Now, researchers at Cardiff University in the UK have used movement and sleep quality data from wearable accelerometers and concluded that they can help identify the disease early, years before clinical diagnosis. Although there is no effective preventive treatment, the authors propose that the tool can determine people at risk of developing Parkinson's disease and identify participants for clinical trials of neuroprotective treatments. The results are published in the journal Nature Medicine.

By directing ultrasound to a specific area of the brain, scientists at the University of Washington have succeeded in inducing a state very similar to hibernation in rats and mice. This state, called "torpor", involves a reduction in metabolism and body temperature to save energy. According to the authors, who publish their results in the journal Nature Metabolism, if it could be applied to humans it could be used in space travel or in medicine, to increase the chances of survival in life-threatening situations such as heart attacks or strokes.

Researchers from FIDMAG Hermanas Hospitalarias and CIBERSAM have announced the development of an algorithm that detects the risk of schizophrenia from fingerprints with a reliability of 70 %. It has been tested on 700 patients with schizophrenia and 850 people without schizophrenia; validation studies are pending.

Research has tested a gene therapy method that targets overactive cells to treat epilepsy in mice. The results are published in the journal Science.

A systematic review and meta-analysis published in JAMA Network Open examines whether there is an association between newborn exposure to SARS-CoV-2 and impaired neurodevelopment compared to those born before the pandemic. Neurodevelopment in the first year of life was not modified by being born or growing up during the covid-19 pandemic or by gestational exposure to SARS-CoV-2. However, the authors appreciated that, regardless of whether maternal infection was present, the pandemic was associated with a risk of delayed communication in these infants.

A US team has successfully integrated brain-like tissue derived from human stem cells into the brains of newborn rats. The research is published in the journal Nature.

A study published today in the Journal of Neurology Neurosurgery & Psychiatry claims that some drugs used to treat attention deficit hyperactivity disorder (ADHD) may also help with some symptoms of Alzheimer's disease.