University of Navarra Clinic

A multidisciplinary study involving several Spanish research groups has preclinically tested a new type of immunotherapy for multiple myeloma. Instead of modifying T cells to attack the tumour directly, as CAR-T cells do, they have managed to make them secrete bispecific antibodies, which bind to the tumour on one side and to other T cells on the other, attracting them to the tumour. According to the authors, this cell therapy was more effective than traditional CAR-Ts and could generate less resistance. The results are published in the journal Science Translational Medicine. 

US researchers have analysed data from 477 people who, using a mobile app, recorded their moods, energy levels and migraine occurrence four times a day for two weeks. Morning attacks were associated with poorer self-rated sleep quality and less energy the day before. Stress and high-energy states were linked to headaches in the afternoon, adds the study, which is published in the journal Neurology.