Raül Andero Galí
ICREA Research Professor, Director of Andero Lab and the Rodent Behavioral Core at the Autonomous University of Barcelona (UAB), and researcher in the Department of Psychobiology and Methodology of Health Sciences at the UAB and at the Carlos III Health Institute, CIBERSAM
It is an interesting study, where the drug amiloride appears to have beneficial effects in treating and preventing the effects of traumatic stressful experiences in mice and their offspring.
The highlight of the study is that the beneficial effects of the drug amiloride appear to persist for three generations in mice. However, the authors do not yet know exactly how this intergenerational transmission of the drug effect may be happening, which detracts from my enthusiasm for the study.
These are very novel results, but they are also preliminary and need to be confirmed and extended by other laboratories to include experiments in humans.