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Reaction to the study analysing the effectiveness of Paxlovid against the omicron variant

A study published in the New England Journal of Medicine has analysed the effectiveness of the antiviral drug Paxlovid after implantation of the omicron variant. The relative risk of severe disease decreased markedly in patients over 65 years of age, both vaccinated and unvaccinated. No differences were found in those under 65 years of age.

24/08/2022 - 23:00 CEST
Expert reactions

Roger Paredes - paxlovid

Roger Paredes

Head of the Infectious Diseases Service at the Germans Trias i Pujol Hospital and senior researcher at the AIDS Research Institute (IrsiCaixa).

Science Media Centre Spain

This is a very important study because until now the data on protection of hospitalisations with Paxlovid had been obtained in patients infected with pre-omicron variants and mostly in unvaccinated patients, so there were doubts as to whether Paxlovid would still be useful in vaccinated people. This study shows that, even in these patients, early treatment prevents severe clinical forms, as long as the patients are at high risk of hospitalisation (over 65 years of age, etc.).

The author has not responded to our request to declare conflicts of interest
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Publications
Nirmatrelvir Use and Severe Covid-19 Outcomes during the Omicron Surge
  • Research article
  • Peer reviewed
  • People
Study types:
  • Research article
  • Peer reviewed
  • People
Topics covid-19
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