Study links consumption of full-fat cheese to lower risk of dementia

People who ate more than 50 grams of high-fat cheese—such as cheddar, brie, or gouda—per day in the 1990s had a lower risk of dementia 25 years later than those who consumed less cheese, according to a study published in Neurology. The study is based on data from more than 27,000 people in Sweden with an average age of 58. The research also shows that those who consumed high-fat cream daily had a lower risk of dementia compared to those who did not consume it.

17/12/2025 - 22:00 CET
Expert reactions

251217 queso demencia tara EN

Tara Spires-Jones

Director of the Centre for Discovery Brain Sciences at the University of Edinburgh, Group Leader in the UK Dementia Research Institute, and Past President of the British Neuroscience Association 

Science Media Centre UK

A new study published by Du and colleagues observed that people who reported a high intake of high fat cheese in the 1990s had lower risk of developing dementia around 25 years later than people who did not eat cheese.  While these are interesting data, this type of study cannot determine whether this association of reduced dementia risk was caused by the differences in cheese consumption. One of the biggest limitations of this study is the cheese consumption as recorded from a food diary and interview at one time point 25 years before the analysis of dementia diagnosis. It is highly likely that diet and other lifestyle factors changed in those 25 years. Strong evidence from across the field indicate that healthy diet, exercise, and cognitively stimulating activities (education, challenging jobs and hobbies etc) can boost brain resilience to diseases that cause dementia. There is not strong evidence for any individual food protecting people from dementia.

Conflicts of interest: "I have no conflicts with this study but have received payments for consulting, scientific talks, or collaborative research over the past 10 years from AbbVie, Sanofi, Merck, Scottish Brain Sciences, Jay Therapeutics, Cognition Therapeutics, Ono, and Eisai, and direct a company Spires-Jones Neuroscience, Ltd to act as a consultant. I am also Charity trustee for the British Neuroscience Association and the Guarantors of Brain and serve as scientific advisor to several charities and non-profit institutions".

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251217 queso demencia naveed EN

Naveed Sattar

Professor of Cardiometabolic Medicine/Honorary Consultant, University of Glasgow

Science Media Centre UK

I do not believe there is a causal link here, as this is an observational study rather than a randomized controlled trial. It is important to note that individuals who consumed more high-fat cheese and cream were, on average, better educated. This raises the possibility of residual confounding - whereby other 'healthy' characteristics associated with higher education, rather than the cheese or cream itself, may explain the lower dementia rates observed. 

We already know of several well-established and proven factors that reduce dementia risk, such as maintaining healthy blood pressure, managing weight, and preventing heart disease or stroke. These interventions should remain the priority, given their strong evidence base, rather than focusing on unproven dietary associations.

Conflicts of interest: "I have consulted for and/or received speaker honoraria from Abbott Laboratories, AbbVie, Afimmune, Amgen, AstraZeneca, Boehringer Ingelheim, Carmot Therapeutics, Eli Lilly, GlaxoSmithKline, Hanmi Pharmaceuticals, Janssen, Menarini-Ricerche, Merck Sharp & Dohme, Metsera, Novartis, Novo Nordisk, Pfizer, Sanofi, and Roche; and received grant support paid to his University from AstraZeneca, Boehringer Ingelheim, Novartis, and Roche. No shares in any medical areas".

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Journal
Neurology
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Authors

Yufeng Du et al. 

Study types:
  • Research article
  • Peer reviewed
  • Observational study
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