physical activity

Although it is well known that physical activity can help reduce the risk of dementia, a study published inThe Lancet Public Health now suggests that context matters. According to a meta-analysis incorporating data from more than four million people, leisure-time exercise — such as walking, cycling, running, swimming or playing sports — is associated with a substantially lower risk of developing dementia. Conversely, physical activity carried out as part of one’s job is linked to a higher risk of developing the condition. As this is an observational study, it does not allow us to determine whether work causes dementia.

A team from China used data from over 17,000 people in the UK Biobank to analyze the relationship between physical activity and cardiovascular risk. Their results indicate that the current minimum recommendation of 150 minutes of moderate-to-vigorous physical activity per week was associated with an 8-9% risk reduction. However, increasing the time to 560-610 minutes was linked to a decrease of more than 30%. According to the authors, who published the study in the British Journal of Sports Medicine, the current recommendations offer universal but modest protection, and optimal benefits would be obtained with substantially higher levels of activity.

Physical inactivity driven by rising temperatures due to climate change could result in between 0.47 and 0.70 million additional premature deaths each year by 2050, according to projections from a new study published in The Lancet Global Health. The study analysed data on the relationship between temperature and physical inactivity across 156 countries between 2000 and 2022. Low- and middle-income countries, where access to air conditioning, the availability of shaded public infrastructure, and discretionary leisure time are limited, were the most affected. Spain is among the European countries expected to be most impacted.

The adoption of policies promoting physical activity has increased over the last two decades, but there is limited evidence that these policies are being implemented, and physical inactivity has remained high during this period, says an article published in Nature Health. The study is based on an analysis of documents from 200 countries and interviews with 46 experts, including one from the ISGlobal research institute in Barcelona.

Moderate-intensity physical activity, such as walking at an average speed of 5 km/h for an additional five minutes per day, is associated with a 10% reduction in all-cause mortality among most adults, according to a study published in The Lancet. The research also found that reducing sedentary time by 30 minutes per day was associated with an estimated 7% reduction in all-cause mortality if adopted by most adults. The study analyzed data from more than 135,000 adults from Norway, Sweden, the United States, and the United Kingdom, with an average follow-up of eight years.

Physical inactivity is a risk factor for the onset of Alzheimer's disease. An international team has studied nearly 300 people with preclinical Alzheimer's—without symptoms but with an accumulation of tau and beta-amyloid proteins in the brain—for 14 years to find out whether physical exercise can also influence its progression. The results indicate that even very moderate activity—walking between 3,000 and 5,000 steps per day—was associated with slower deterioration, while the benefits—which appear to be related to lower tau protein deposits—were greater and tended to stabilise with activity involving between 5,000 and 7,500 steps. The results are published in the journal Nature Medicine.

Analysis of data from a mobile health app covering more than 5,000 people in 1,609 cities in the United States reveals that moving from a less walkable area to a more walkable area leads to an increase in the number of steps taken per day, and vice versa. Walkability was measured using the Walk Score, an index based on parameters such as proximity to services, block length and intersection density. According to the authors, the results can serve as a guide for urban design policies that improve public health. The study is published in Nature.

In marathon runners, the myelin content of specific regions of the brain is reversibly reduced, according to a study carried out in the Basque Country. This observation is consistent with animal evidence suggesting that myelin lipids - a substance that surrounds neurons - can act as energy reserves in extreme metabolic conditions, as detailed by the authors in Nature Metabolism. The analysis is based on magnetic resonance imaging of eight men and two women before and after running a marathon. According to the study, the myelin content was fully recovered two months after the race.

A study published in the journal PLOS ONE, which includes data from over 3,000 Spanish adolescents and children, has shown that those living in more walkable areas report spending more minutes per day engaging in active transportation compared to those from less walkable neighborhoods. Along those lines, the lowest average minutes spent playing outdoors are observed among participants from neighborhoods with lower socioeconomic status and less walkability. The research is part of the PASOS study, coordinated by the Gasol Foundation.

Research involving more than 3,000 adolescents and children from all Spanish autonomous communities concludes that those living in less walkable neighbourhoods with lower socioeconomic status walk less and engage in less physical activity at weekends than those living in more walkable areas with higher socioeconomic status. The paper, published in the journal PLOS ONE and part of the PASOS study, was presented by two of its authors at a briefing organised by SMC Spain.