Cristina García Frigola
We have just learned that this year’s Nobel Prize in Medicine or Physiology has been awarded to researchers Karl Deisseroth, Peter Hegemann, and Georg Nagel “for their discoveries concerning light-activated ion channels and optogenetics.”
This came as no surprise, given that their discoveries have revolutionized neuroscience research. The use of light-sensitive ion channels, expressed in specific populations of cells in the brain, allows us to control their activity with unprecedented spatial and temporal resolution.
This sophisticated technology enables us to activate and deactivate specific neural circuits, thereby characterizing their functions in the brain. It has become an essential tool for studying the brain, as well as for identifying the origins of neurological and psychiatric disorders, opening up new therapeutic possibilities.