Reacción a "A stem cell transplant with only one protective mutation achieves remission of HIV in a cancer patient"

It is a very high-quality study that has a significant impact. Of the reported cases of “cure,” virtually all except the “Geneva patient” had the Delta 32 mutation. This patient and the heterozygote now being published are the exception, although the important thing is that they open the door to these transplants without the donor being Delta 32 homozygous.

There are also very important limitations. Although these patients are important proof of concept that HIV infection can be eradicated, these cases cannot be generalized. All of them are patients with neoplasia, usually hematological, undergoing very aggressive treatments whose complications can sometimes be fatal. It would not be logical or ethical to subject a patient to such aggressive therapies if they did not have a serious underlying neoplasia.