animal health

An analysis carried out in the United States has shown that, through intensive breeding and artificial selection, humans have pushed breeds such as pugs and Persian cats to evolve with very similar skulls and flattened faces. These two species, which have a common ancestor but have been evolutionarily separated for 50 million years, have converged to the point where they resemble each other more than they do members of their own species or their ancestors. According to the study, published in PNAS, ‘this phenomenon has not been observed before in domesticated species.’ The authors lament that humans ‘have bred brachycephalic breeds to such an extreme that they are prone to respiratory, feeding and birthing problems and would not survive in the wild.’

A team in the US has tested the efficacy of baloxavir, an antiviral already on the market for treating common flu, against avian influenza in mice. The results, published in the journal Nature Microbiology, show that it is more effective than the currently recommended oseltamivir (Tamiflu) except when the infection is via the mouth, in which case it is equally effective. According to the authors, baloxavir ‘could be considered for the potential treatment of serious H5N1 virus infections in humans’.

Peto´s paradox is the lack of observed relationship between the size of an animal and the prevalence of cancer, despite the fact that the greater number of cells and divisions as they get larger should increase the likelihood of cancer. A new study disproves this paradox by finding that, at least in terrestrial vertebrates, larger species do develop more cases of cancer. In quite a few of them, however, the increase is less than would be expected, suggesting that they have evolved anticancer mechanisms that remain worth studying. The results are published in the journal PNAS.  

The H5N1 avian influenza virus can be transmitted between mammals, according to a study published in Nature. The research team isolated the virus from the milk of an infected cow in New Mexico (USA) and found that it spreads in mice and ferrets, reaching the mammary glands of both animals. In addition, the virus was also transmitted from infected lactating mice to their offspring. The European Centre for Disease Prevention and Control (ECDC) has issued a press release on Monday recommending increased surveillance for these viruses.

Dogs and other pets can be sentinels for human health, two US researchers argue in the journal Science. Because they share the same environment as their owners, dogs can help study, for example, the epidemiology of vector-borne pathogens, the effects of exposure to heavy metals and endocrine disruptors, and even the effects of social adversity. Improving canine data collection would help assess the health of people who cohabit with dogs, the authors argue. 

In an anonymous online survey of dog owners in Denmark, 38% of respondents said they administered cannabinoid products - such as cannabidiol drops - to their pets without a prescription, even though their use is not legal in animals. Reasons given included pain, behavioural problems and allergies in their dogs. Some 2,000 people responded to the survey, the results of which are published in the journal PLoS ONE.

The vast majority of mammals remain fertile until the end of their lives. Humans and some species of whales deviate from that norm and do go through menopause. Now, research published in Science reveals that menopause exists in female chimpanzees, too, and that it lasts for a fifth of their adult lifespan. To reach these conclusions, the research team observed 185 female chimpanzees between 1995 and 2016 in Uganda's Kibale National Park and measured hormone levels in urine samples from specimens of various ages.

A review examines the role of domestic and semi-domestic animals, such as cats, in the emergence of potential zoonoses due to their close contact with humans. The paper, published in the journal Science Translational Medicine, concludes that companion animal health risks will become increasingly problematic with climate change and rapid urbanisation.

Since the first case of epizootic haemorrhagic disease (EHD) in Spain was detected in cattle in November 2022, it has spread among farms in several autonomous communities in dozens of outbreaks. The mosquito-borne disease does not affect humans, but has the potential to cause economic losses.

The EMA's annual European Surveillance of Veterinary Antimicrobial Consumption (ESVAC) report shows that sales of antibiotics for animal use have decreased by 47% between 2011 and 2021. In addition, sales of antibiotics considered "critically important" for use in humans have also decreased.