People who have a parent, sibling, or step-sibling with major depression have a higher risk of major depression themselves, according to research based on data from 2.9 million people in Denmark. This risk increases with the number of affected relatives and when exposure to depression occurs in childhood and adolescence, but does not vary by sex or kinship, says the study published in JAMA Psychiatry.
Research concludes that different types of antidepressants are capable of generating resistance to multiple antibiotics, even when administered for short periods of time. The results are published in the journal PNAS.
Physical activity is associated with significant reductions in depressive symptoms in children and adolescents, according to a systematic review and meta-analysis published in JAMA Pediatrics that included 21 studies with 2,400 participants. The largest decreases in these symptoms were found in those aged 13 years and older.
Two studies published in the journal Nature Communications have found specific characteristics in the microbiota of people with depression, including populations of different ethnicities and habits.
A phase 2 clinical trial has examined the use of the hallucinogen psilocybin in different amounts for the treatment of resistant depression. The results are published in the New England Journal of Medicine.
A study published today in the journal PLoS ONE examines the effectiveness of antidepressant treatments in improving patients' quality of life over time.