A genomic analysis of monkeypox viruses from patients in the ongoing outbreak reveals that it most likely has a single origin. This 2022 monkeypox virus diverges from those of 2018-2019 in many more genetic variations than expected for Orthopoxviruses, which may represent ongoing accelerated evolution, according to the authors. The study is published in Nature Medicine.
A study published in The Lancet Infectious Diseases analyses the response of seven monkeypox patients diagnosed in the UK between 2018-2021, treated with the antivirals brincidofovir and tecovirimat.
On 18 May, the Ministry of Health confirmed to SMC Spain that eight suspected cases "clinically compatible" with monkeypox had been detected. The same afternoon, the Consejería de Sanidad de la Comunidad de Madrid reported that it had detected 23 possible cases of infection. These cases need to be confirmed after testing. At least 7 cases have been confirmed in the UK and Portugal. This is a rare zoonotic viral disease and there is no vaccine or specific treatment available. Treatment is symptomatic and supportive. Most cases are resolved favourably.
Following the detection of several cases of people infected with the simian smallpox virus in the UK, health authorities are concerned that there may be EU-wide transmission with undetected infections, both within and outside the country. In Spain, the Community of Madrid has identified 23 possible cases of infection.