Óscar de la Calle-Martín

Óscar de la Calle-Martín

Óscar de la Calle-Martín
Cargo

Specialist in Immunology at the Hospital de Sant Pau in Barcelona and secretary of the Spanish Society of Immunology.

Topics

Reactions: tobacco alters the immune response even in the long term

A study has analysed more than 100 environmental factors and their impact on the immune response. After studying about a thousand volunteers, its conclusions are that smoking is the factor that causes the most alterations in defences. While some changes are transient, others may remain for years after quitting. The results are published in the journal Nature.

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Reactions: Clinical trial tests gene therapy in severely immunodeficient children

Bubble boy syndrome is a very serious condition caused by combined immunodeficiency. It is sometimes caused by certain mutations in the gene that codes for the Artemis protein. A phase I-II clinical trial has tested a gene therapy that adds a correct copy of the gene. The results are published in the journal NEJM.

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