Ramón y Cajal Hospital

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SMC participants

Neurologist at the CSUR Multiple Sclerosis Unit of the Ramón y Cajal University Hospital and member of the Ramón y Cajal Institute for Health Research

Dermatologist specializing in vitiligo at the Ramón y Cajal Hospital in Madrid.

Dermatologist at the Hospital Ramón y Cajal and Master in Tropical Medicine at the Universidad Autónoma de Madrid, member and one of the spokespersons of the Spanish Academy of Dermatology and Venereology (AEDV) for monkeypox

Researcher at the Ramón y Cajal Hospital. Member of the Specialised Group for the Study of the Human Microbiota of the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC-GEMBIOTA).

Contents related to this centre

After the first year of life, the father's contribution to his baby's microbiota is comparable to the mother's contribution, whether born vaginally or by caesarean section, says a study published in Cell Host & Microbe. In addition, faecal microbiome transplants from the mother to her baby can restore the microbiome in the case of caesarean birth, says the study, which included 74 babies and involved Spanish participants. 


Researchers have found specific antibodies in the blood of patients years before they showed symptoms of multiple sclerosis. This group of antibodies was present in 10% of the 250 people who later developed the disease, and were part of a sample of over 10 million US military personnel. The finding could have potential for early detection of multiple sclerosis, says the research team in a paper published in Nature Medicine


Two studies have found changes in the microbiome of patients affected by chronic fatigue syndrome. In particular, they have found a decrease in both butyrate and certain bacteria that produce butyrate. Butyrate is a factor related to the protection of the intestinal barrier and appears to play a role in the regulation of the immune system. Both papers are published in the journal Cell Host and Microbe.


An international team including researchers from Spain has analysed the level of exchange of microbial strains between different generations (vertical transmission) and between people who share a household or are close contacts (horizontal transmission). The analysis, published in the journal Nature, is based on about 9,700 microbiome samples from the faeces and saliva of people with different lifestyles from countries. According to the research, the transmission of bacteria is more frequent for the mouth microbiome than for the gut microbiome among people living together.   


The establishment of the baby's microbiota occurs around the time of birth, when it receives bacteria directly from the mother. A study in the journal Cell suggests that genes can also be transmitted between them by horizontal transfer, without the need for the passage of these micro-organisms.


Two studies published in the journal Nature Communications have found specific characteristics in the microbiota of people with depression, including populations of different ethnicities and habits.


A double clinical trial has analyzed the efficacy of ruxolitinib cream in treating depigmentation associated with vitiligo. The results are published in the New England Journal of Medicine.


Today the World Health Organisation declared smallpox a Public Health Emergency of International Concern. The move was announced at a press conference by its director general, Tedros Adhanom, despite a lack of consensus in the International Health Regulations Emergency Committee.


The first study of UK cases of the current monkeypox outbreak finds differences between the symptoms of these patients and those of previous outbreaks in other parts of the world. The work is published in the journal The Lancet Infectious Diseases.


Investigadores del banco público de heces Openbiome (EE UU) procesan las donaciones fecales para enviarlas a hospitales de todo el país como tratamiento de la diarrea recurrente causada por C. difficile. / Openbiome

The rise in cases of asthma, allergies and digestive tract diseases, among others, could be linked to changes in the microbiome. US researchers are propose to combat this trend by having us all save samples of our own gut microbiota when we are young and healthy, for later use in an autologous faecal microbiota transplant.