Sevilla University

The seventh Annual Report of the COSCE Transparency Agreement, prepared by the European Animal Research Association, which analyses transparency in the use of animals for scientific experimentation in Spain in 2023, was presented today. According to the document, transparency is consolidated among the signatory institutions -168 in 2024- and all of them publish a statement on their websites on the use of animals. Public mention of the number and species used stands at 47%, compared to 38% the previous year.

The Karolinska Institute has awarded the Nobel Prize in Medicine or Physiology to Victor Ambros and Gary Ruvkun for the discovery of microRNAs, small RNA fragments that do not contain instructions for making proteins but instead participate in the regulation of gene expression. Their role is fundamental in processes such as cell differentiation, and their alteration can influence diseases like cancer.

Parkinson's disease is usually diagnosed when there is already extensive neuronal damage and symptoms are evident. Now, researchers at Cardiff University in the UK have used movement and sleep quality data from wearable accelerometers and concluded that they can help identify the disease early, years before clinical diagnosis. Although there is no effective preventive treatment, the authors propose that the tool can determine people at risk of developing Parkinson's disease and identify participants for clinical trials of neuroprotective treatments. The results are published in the journal Nature Medicine.

A study in mice found that a molecule called TDI-11861 works as an oral male contraceptive, temporarily blocking sperm function. The paper, published in Nature Communications, presents the research as a step towards an on-demand male contraceptive drug: the user could take a birth control pill before sex and become fertile again the next day. Four co-authors of the study have founded a company in the US to develop such products. 

Beta-blockers (β-blockers) are drugs to treat heart conditions that are also used for anxiety. According to research published in PLOS Medicine, periods of treatment with these drugs are associated with a lower risk of being charged by the police with a violent crime - a 13% lower risk than periods without treatment. The research, which included nearly 1.5 million people in Sweden between 2006 and 2013, does not support the use of these drugs to treat anxiety.

Research concludes that different types of antidepressants are capable of generating resistance to multiple antibiotics, even when administered for short periods of time. The results are published in the journal PNAS.

Some 4,000 engraved slate plaques resembling owls have been found in tombs and graves on the Iberian Peninsula dating back to the Copper Age. It has been speculated that they may have had a ritual significance. Spanish scientists have analysed 100 of these plaques and propose, in an article published in Scientific Reports, that they may have been carved by children for play.

The Ministry of Health has announced the purchase of 10 proton therapy equipment for public hospitals of the National Health System in seven autonomous communities. They will be used to treat tumours, especially in paediatric patients. The cost of the equipment will be financed by the Amancio Ortega Foundation.

Ukrainian mathematician Maryna Viazovska was today awarded one of four Fields Medals, considered the Nobel Prize in mathematics. After Iran's Maryam Mirzakhan, who received it in 2014, she is the second woman to be honoured with this prestigious award.

Mathematician Maryna Viazovska (Kiev, Ukraine; 1984) has today been awarded one of the four Fields Medals, considered the Nobel Prize in Mathematics. She is the second woman to be awarded this prize, after the Iranian Maryam Mirzakhan, who received it in 2014.