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Cell-free DNA (cfDNA) sequencing analysis for fetal aneuploidies - chromosomal abnormalities - can incidentally detect maternal cancer, according to a study published in NEJM. Researchers screened 107 pregnant and postpartum mothers with no symptoms of cancer, but who had received unusual clinical cfDNA sequencing results, for cancer. In this sample, cancer was present in 48% of the women.
Most cases of autism have no known cause. Now, a study led at IRB Barcelona has discovered a mechanism that could explain a good part of these situations. The loss of a few amino acids in a crucial protein would affect the activity of hundreds of genes and the development of neurons. To explain the study, which is published in the journal Nature and which could open the door to future treatments, the Science Media Centre Spain organized an informative session with Raúl Méndez and Xavier Salvatella, the two scientists who have led the research.
A paper published in Nature presents a machine learning model capable of producing reliable probabilistic weather forecasts. The model, called GenCast, outperforms the most efficient traditional medium-range weather forecasting and is also able to better predict extreme weather, tropical cyclone tracks and wind energy production.
In three to six years, the first ice-free day in the Arctic could occur if a series of extreme weather events - such as an unusually warm autumn, winter and spring in the region - occur, according to a study comparing various models and scenarios in Nature Communications. An ice-free day refers to a day with Arctic Ocean ice coverage of less than 1 million square kilometres; the average coverage was 6.85 million square kilometres between 1979 and 1992.
According to a study published in Nature Medicine, deep brain stimulation of the lateral hypothalamus improves walking and promotes recovery in humans and rodents with spinal cord injuries. In humans, the authors tested this technique on two patients who relied on assistive devices and had difficulty walking; both showed improved performance in the ten-meter and six-minute walking tests. Combined with rehabilitation, the patients experienced recovery that persisted even after the deep brain stimulation was turned off.
The seventh Annual Report of the COSCE Transparency Agreement, prepared by the European Animal Research Association, which analyses transparency in the use of animals for scientific experimentation in Spain in 2023, was presented today. According to the document, transparency is consolidated among the signatory institutions -168 in 2024- and all of them publish a statement on their websites on the use of animals. Public mention of the number and species used stands at 47%, compared to 38% the previous year.
The fifth session of the United Nations Intergovernmental Negotiating Committee to develop an international legally binding instrument on plastic pollution (INC-5) ended without a treaty in Busan, South Korea, in the early hours of the morning. The more than 100 countries participating in what was to be the final round of negotiations have agreed to continue negotiating, reports Reuters.
In the context of World AIDS Day, which is celebrated on 1 December, it is essential to reflect on one of the most urgent challenges in the fight against this disease: HIV in the paediatric population. A project led by the Complutense University of Madrid seeks to reduce paediatric mortality by training research leaders in sub-Saharan Africa and applying technology and innovation.
According to a study published in Science, social media content containing misinformation provokes more moral outrage than content containing accurate information, and this outrage facilitates the spread of misinformation. In addition, the results also showed that people are more likely to share this outrage-provoking misinformation without reading it first.
At least two hominin species - Homoerectus and Paranthropus boisei- coexisted in Kenya's Turkana Basin around 1.5 million years ago, a study published in Science confirms. The authors describe the first physical evidence of this coexistence in the form of footprints, found at several sites in the area.